Coumadin is an anticoagulant which is used to prevent the blood from clotting. You should inform
the doctor if you have any bleeding disorder before taking this medicine and you should be aware of
the possible side effects of this medicine. Close monitoring of liver and kidney function is
necessary while receiving this medicine due to an increase in the risk of bleeding.
Uses of Coumadin
Deep Vein Thrombosis.
Coumadin is used to prevent the blood clot formation in legs and other extremities.
Pulmonary Embolism.
Coumadin is used in the treatment of Pulmonary embolism (blood clot in the lung) by
improving the blood flow in the lungs.
Prophylaxis for Myocardial Infarction.
Coumadin is used to prevent the formation of clots in vessels that supply blood to the
heart. This helps in preventing a heart attack.
Prevention of Thromboembolism in Atrial Fibrillation.
Coumadin is used to prevent blood clot formation in patients with heart disorders like
atrial fibrillation (irregular heartbeat).
General Instructions
Take Coumadin as advised by the doctor. Do not consume larger quantities than prescribed. This
medicine is not recommended in patients with gastrointestinal bleeding, head injury, and low blood
platelets level. Patients with liver injury/disease are advised to consult the doctor before taking
this medicine.
Missed Dose
Take the missed dose as soon as you remember. If it is almost the time for your next scheduled
dose, then the missed dose should be skipped.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
How it works
It prevents the blood from clotting by stopping the action of clotting factors.
Safety Information.
Side effects
The most common possible side effects:
Abdominal pain
Blurred vision
Blood in urine and stools
Headache
Dizziness
Diarrhea
Skin rash and itching
Yellow colored eyes or skin
Muscle or joint pain
Excessive air or gas in stomach
Hair loss or thinning of the hair
When not to use
Allergy
Coumadin is not recommended for use in patients with a known allergy to Coumadin.
Central nervous system bleeding
Coumadin is not recommended for use in patients with a head and/or spinal cord injury.
Bleeding disorder
Coumadin is not recommended for use in patients who have a known history of bleeding
disorders or an active bleeding disorder (inability of the blood to clot normally).
Gastrointestinal disorders
Coumadin is not recommended for use in patients with a known history of gastrointestinal
disorders like peptic ulcer disease or gastrointestinal bleeding due to an increase in the
risk of further bleeding.
General warnings
Bleeding
Coumadin is known to cause severe bleeding. It is not recommended in patients with
conditions like gastrointestinal bleeding, head injury, and patients about to undergo a
surgery. Any symptoms of blood in the stools, vomiting blood, or blood in the urine should
be reported to the doctor on priority. Close monitoring of prothrombin time is necessary
while receiving this medicine.
Tissue Necrosis
Coumadin may cause tissue death within a few days of the treatment. Close monitoring of
symptoms like pain and change in skin color is necessary while receiving this medicine. It
is advised to stop the treatment if these symptoms appear. An alternate treatment option
should be considered based on the clinical condition.
Calciphylaxis
Coumadin may cause a rare reaction called Calciphylaxis in which calcium is accumulated in
small blood vessels of the fat and skin tissues. Close monitoring of symptoms like pain and
change in skin color is necessary while receiving this medicine. It is advised to stop the
treatment if these symptoms appear. An alternate treatment option should be considered based
on the clinical condition.
Warnings for special population
Pregnancy
Coumadin is not recommended for use in pregnant women except in life-threatening
conditions where the potential benefits outweigh the risks. Discuss all the risks and
benefits with your doctor before taking this medicine.
Breastfeeding
Coumadin is recommended for use in breastfeeding women only if clearly needed. The risks
and benefits should be discussed with the doctor before taking this medicine. If the
medicine is used, close monitoring of the infant for any undesired effects is necessary.
Interaction with medicines
Coumadin can interact with the following medicines:
Ethinyl Estradiol
Aspirin
Proton pump inhibitors
Fluoroquinolone antibiotics
Disease interactions
Bleeding disorders
Coumadin is not recommended in patients with a history of bleeding disorders or an active
bleeding disorder (inability of the blood to clot normally) due to an increase in the risk
of further bleeding. Replacement with a suitable alternative should be done under your
doctor's supervision.
Liver Disease
Coumadin is not recommended in patients with a liver injury/disease due to an increase in
the risk of bleeding. Close monitoring of liver function and symptoms like blood in the
urine and stools, dizziness, unusual bleeding, etc. is necessary while receiving this
medicine.
F.A.Q.
Q: What Coumadin is used for?
A: Coumadin is used to treat or prevent blood clots in veins or arteries, which can reduce the
risk of stroke, heart attack, or other serious conditions.
Q: How should I take Coumadin?
A: Take Coumadin as advised by the doctor. Do not consume larger quantities than prescribed.
This medicine is not recommended in patients with gastrointestinal bleeding, head injury, and low
blood platelets level. Patients with liver injury/disease are advised to consult the doctor before
taking this medicine.
Q: What should I do if I miss the dose?
A: Take the missed dose as soon as you remember. If it is almost the time for your next
scheduled dose, then the missed dose should be skipped.
See Also.
Inderal
Propranolol
Inderal is indicated for the treatment of tremors, angina (chest pain), hypertension (high blood pressure),
heart rhythm disorders, and other heart or circulatory conditions. It is also used to treat or prevent heart
attack, and to reduce the severity and frequency of migraine headaches.
Aquazide
Hydrochlorothiazide
Aquazide is a diuretic and antihypertensive drug used to treat edema associated with certain health conditions, like heart failure or renal dysfunction among others, and manage elevated blood pressure (hypertension). Suitable for patients of all ages.
Aldactone
Spironolactone
Aldactone is a diuretic which is used to control high blood pressure and edema. It is usually taken once
daily, preferably in the daytime, to prevent sleep disturbances. Frequent monitoring of blood pressure and
electrolytes level is necessary.
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